Finance Facts and Figures

Small and Medium Sized Biotechnology Companies (“biotech SMEs”) play an important role in the discovery and development of new technologies and products in the life sciences.  Without the intervention of biotech SMEs during the past two decades, there would certainly have been less progress in the development of medicines for unmet medical needs or in the development of new agri-food processes and products.  Europe currently counts over 1,900 innovative biotech SMEs, which all have the potential to become key drivers of public welfare and economic growth, but which also have high requirements in terms of capital, business environment, people, and public and political support.

In 2006* 

Europe

US

Number of companies

2330

1991 

Number of new companies formed 

131

78

Number of employees

98,500  

190,500

R & D expenditure

€7.6 billion  

€21 billion

Revenue

€21.5 billion  

€41.5 billion

Venture Capital raised

€1.02 billion  

€3.2 billion

Equity raised

€3.65 billion

€11.3 billion

Debt raised  

€0.81 billion

€7.4 billion

*Source: Critical I (data collected from dedicated biotech companies)

In 2007* 

Europe

North America

Venture Capital raised

€ 1.2 billion

€ 4.0 billion

Percent of companies that closed or failed to find a listed industry buyer or achieve an IPO 

42%

 

28%

Percentage of companies that raised more than €50 million before IPO listing

28%

 

56%

Active lead investors per company

0.9

0.5

*Source: IPEEX (data collected from healthcare biotech companies)

In conclusion

European companies

Europe needs

  • Take longer to raise capital

  • Have more defaults & private consolidation

  • Have fewer ‘meaningful’ IPOs

  • Remain sub-critical size

  • Are part of a smaller industry due to lower amounts of capital available

…compared to N. American counterparts

  • More lead investors

  • More inter-regional lead investment

  • Weak companies to fail faster (and therefore consolidate) with greater comfort

  • Strong companies to fund faster with far greater lead investor choice

European biotech SMEs: from money to critical mass 

Today, one of the main barriers in Europe to successful entrepreneurship, innovation and product development is the lack of different forms of finance along the ‘capital chain’ (i.e. from seed capital to IPO and secondary offerings). Besides the European market fragmentation, the lack of available capital (i.e. EU-money invested in European companies) has a great impact on the economic and industrial evolution of the European biotech industry.  With approximately the same number of companies as in the European sector, the US biotechnology industry employs almost twice as many people, spends almost 3 times as much on R&D, raises 3 or 4 times as much venture capital, and has access to 4 times as much debt finance.  Furthermore, the US industry generates roughly twice the revenue of the European sector (€42 billion versus €22 billion). 

For more detailed global and intra-European comparative industry figures, also see the Critical I report: Biotechnology in Europe: 2006 Comparative Study.

 


 

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