Nominated by: Pfizer
In March 2020, the WHO declared COVID-19 a pandemic. At “lightspeed,” Pfizer collaborated with BioNTech, a German-based company, to develop an mRNA-based vaccine. The companies moved with urgency, without compromising their high standards for safety, quality, or integrity. Through a rigorous clinical trial programme and extensive discussions with regulators, the vaccine candidate BNT162b2 advanced rapidly.
In November, Pfizer and BioNTech announced that BNT162b2 had been shown to be 95% effective against COVID-19 in their Phase 3 trial. This advance could not have happened without the partnership of Pfizer and BioNTech, along with the leadership of Pfizer’s Kathrin Jansen, who herself emigrated from Germany.
BNT162b2 is one of the most significant scientific advancements in the past century, helping both to protect communities from COVID-19 and pave the way for a return to normalcy. Pfizer plans to deliver >2.5 billion doses worldwide in 2021 and next generation vaccine formulations are in development to potentially increase access. Trials in special populations, including pregnant women and young children, have also been initiated.
It is important to recognize this remarkable outcome has far reaching implications for research and development. The vaccine crystalized the scientific potential of mRNA technology, which Pfizer is now expanding into other areas in hopes of preventing and treating other serious, life-threatening diseases.